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UKPDS研究報告
英國糖尿病研究報告 (The United Kingdom Prospective Diabetes Study) 於一九九九年發表了一篇長達十一年之糖尿病二型及其併發症之研究報告。
- 此項研究顯示，每降低1%的糖化血紅蛋白 (HbA1c) (例如由9%降至8%)，微細血管的病變率可降低35%。
- 二型的糖尿病患者如果長期控制血糖於理想水平，能有效減低、延遲視網膜病、腎病之併發症發生及惡化之機會。
Reference:
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UK Prospective Diabetes Study Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352:837-853, 1998 |
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UK Prospective Diabetes Study Group: Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 352:854-865, 1998 |
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UK Prospective Diabetes Study Group: Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes (UKPDS 38). BMJ 317:703 -713, 1998 |
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UK Prospective Diabetes Study Group: Efficacy of atenolol and captopril in reducing risk of both macrovascular and microvascular complications in type 2 diabetes (UKPDS 39). BMJ 317:713 -720, 1998 |
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